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1

Trends in vaccine adjuvants

Schijns, Virgil EJC, Lavelle, Ed C

Journal:

Expert Review of Vaccines

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

2

Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles

Lebre, F., Pedroso de Lima, M.C., Lavelle, Ed C., Borges, O.

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

3

Nlrp-3-Driven Interleukin 17 Production by γδT Cells Controls Infection Outcomes during Staphylococcus aureus Surgical Site Infection

Maher, Belinda M., Mulcahy, Michelle E., Murphy, Alison G., Wilk, Mieszko, O'Keeffe, Kate M., Geoghegan, Joan A., Lavelle, Ed C., McLoughlin, Rachel M., Morrison, R. P.

Journal:

Infection and Immunity

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

4

Novel adjuvants and delivery systems for HIV vaccines

OʼHagan, Derek T., Lavelle, Ed

Journal:

AIDS Supplement

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

5

Advances in immunotherapy for the treatment of glioblastoma

Tivnan, Amanda, Heilinger, Tatjana, Lavelle, Ed C., Prehn, Jochen H. M.

Journal:

Journal of Neuro-Oncology

Year:

2017

Language:

english

File:

PDF, 954 KB

english, 2017

6

The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation

Lebre, Filipa, Sridharan, Rukmani, Sawkins, Michael J., Kelly, Daniel J., O’Brien, Fergal J., Lavelle, Ed C.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.85 MB

english, 2017

7

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Clancy, Danielle M., Sullivan, Graeme P., Moran, Hannah B.T., Henry, Conor M., Reeves, Emer P., McElvaney, Noel G., Lavelle, Ed C., Martin, Seamus J.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.54 MB

english, 2018

8

Exfoliation in Endotoxin-Free Albumin Generates Pristine Graphene with Reduced Inflammatory Properties

Lebre, Filipa, Hanlon, Damien, Boland, John B., Coleman, Jonathan, Lavelle, Ed C.

Journal:

Advanced Biosystems

Year:

2018

Language:

english

File:

PDF, 4.64 MB

english, 2018

9

Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming

McEntee, Craig P., Moran, Hannah B.T., Muñoz-Wolf, Natalia, Liddicoat, Alex M., Carroll, Elizabeth C., Erbo-Wern, Jeanette, Coulter, Ivan S., Andersen, Peter, Follmann, Frank, Lavelle, Ed C.

Journal:

Year:

2019

Language:

english

File:

PDF, 810 KB

english, 2019

10

The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants

James Harris, Fiona A. Sharp, Ed C. Lavelle

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 193 KB

english, 2010

11

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

Caroline E. Sutton, Stephen J. Lalor, Cheryl M. Sweeney, Corinna F. Brereton, Ed C. Lavelle, Kingston H.G. Mills

Journal:

Year:

2009

Language:

english

File:

PDF, 695 KB

english, 2009

12

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

Alexander U. Lüthi, Sean P. Cullen, Edel A. McNeela, Patrick J. Duriez, Inna S. Afonina, Clare Sheridan, Gabriela Brumatti, Rebecca C. Taylor, Kristof Kersse, Peter Vandenabeele, Ed C. Lavelle, Seamus

Journal:

Year:

2009

Language:

english

File:

PDF, 2.22 MB

english, 2009

13

Response: Characteristics of IL-17-Producing γδ T Cells

Caroline E. Sutton, Stephen J. Lalor, Cheryl M. Sweeney, Corinna F. Brereton, Ed C. Lavelle, Kingston H.G. Mills

Journal:

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

14

The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses

Andres Mori, Ewa Oleszycka, Fiona A. Sharp, Michelle Coleman, Yuki Ozasa, Manmohan Singh, Derek T. O'Hagan, Lidia Tajber, Owen I. Corrigan, Edel A. McNeela, Ed C. Lavelle

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

15

Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase

Clare C. Cunningham, Evanna Mills, Lisa A. Mielke, Laura K. O'Farrell, Ed Lavelle, Andrés Mori, Geraldine M. McCarthy, Kingston H.G. Mills, Aisling Dunne

Journal:

Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 894 KB

english, 2012

16

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Inna S. Afonina, Graham A. Tynan, Susan E. Logue, Sean P. Cullen, Michael Bots, Alexander U. Lüthi, Emer P. Reeves, Noel G. McElvaney, Jan P. Medema, Ed C. Lavelle, Seamus J. Martin

Journal:

Year:

2011

Language:

english

File:

PDF, 2.03 MB

english, 2011

17

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O'Neill, Luke A J, Hollyfie

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

18

Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

Cullen, Sean P., Henry, Conor M., Kearney, Conor J., Logue, Susan E., Feoktistova, Maria, Tynan, Graham A., Lavelle, Ed C., Leverkus, Martin, Martin, Seamus J.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.63 MB

english, 2013

19

Delivery systems and adjuvants for oral vaccines

Lavelle, Ed C, O’Hagan, D T

Journal:

Expert Opinion on Drug Delivery

Year:

2006

Language:

english

File:

PDF, 696 KB

english, 2006

20

Immunomodulatory properties of the vaccine adjuvant alum

Oleszycka, Ewa, Lavelle, Ed C

Journal:

Current Opinion in Immunology

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

21

The synthesis and biological evaluation of mycobacterial p-hydroxybenzoic acid derivatives (p-HBADs)

Bourke, Jean, Brereton, Corinna F., Gordon, Stephen V., Lavelle, Ed C., Scanlan, Eoin M.

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 527 KB

english, 2014

22

NLRP3 in protective immunity and vaccination against respiratory infection

Lavelle, Ed C, McNaughton, Anne, McNeela, Edel

Journal:

Expert Review of Vaccines

Year:

2011

Language:

english

File:

PDF, 644 KB

english, 2011

23

Harnessing the antibacterial and immunological properties of mucosal-associated invariant T cells in the development of novel oral vaccines against enteric infections

Abautret-Daly, Aine E., Davitt, Christopher J.H., Lavelle, Ed C.

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014

24

Functionalization of Carbon Nanoparticles Modulates Inflammatory Cell Recruitment and NLRP3 Inflammasome Activation

Yang, Marie, Flavin, Kevin, Kopf, Ilona, Radics, Gabor, Hearnden, Claire H. A., McManus, Gavin J., Moran, Barry, Villalta-Cerdas, Adrian, Echegoyen, Luis A., Giordani, Silvia, Lavelle, Ed C.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.88 MB

english, 2013

25

Carbon Nanotubes: Functionalization of Carbon Nanoparticles Modulates Inflammatory Cell Recruitment and NLRP3 Inflammasome Activation (Small 24/2013)

Yang, Marie, Flavin, Kevin, Kopf, Ilona, Radics, Gabor, Hearnden, Claire H. A., McManus, Gavin J., Moran, Barry, Villalta-Cerdas, Adrian, Echegoyen, Luis A., Giordani, Silvia, Lavelle, Ed C.

Journal:

Year:

2013

File:

PDF, 1.05 MB

2013

26

All things mucosal

Thanavala, Yasmin, Lavelle, Ed, Ogra, Pearay

Journal:

Expert Review of Vaccines

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

27

Targeted mucosal delivery of drugs and vaccines

Journal:

Expert Opinion on Therapeutic Patents

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

28

Delivery strategies to enhance oral vaccination against enteric infections

Davitt, Christopher J.H., Lavelle, Ed C.

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 2.29 MB

english, 2015

29

Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines

Armstrong, Michelle E., Lavelle, Ed C., Loscher, Christine E., Lynch, Marina A., Mills, Kingston H. G.

Journal:

The Journal of Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 1012 KB

english, 2005

30

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

Ross, Pádraig J., Sutton, Caroline E., Higgins, Sarah, Allen, Aideen C., Walsh, Kevin, Misiak, Alicja, Lavelle, Ed C., McLoughlin, Rachel M., Mills, Kingston H. G., Harvill, Eric T.

Journal:

Year:

2013

Language:

english

File:

PDF, 846 KB

english, 2013

31

Mucosal immunity on the banks of the Duoro

Lavelle, Ed C., Thanavala, Yasmin, Ogra, Pearay

Journal:

Year:

2009

Language:

english

File:

PDF, 753 KB

english, 2009

32

IL-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination

Oleszycka, Ewa, Moran, Hannah B.T., Tynan, Graham A., Hearnden, Claire H., Coutts, Graham, Campbell, Matthew, Allan, Stuart M., Scott, Christopher J., Lavelle, Ed C.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.73 MB

english, 2016

33

A novel adjuvanted capsule based strategy for oral vaccination against infectious diarrhoeal pathogens

Davitt, Christopher J.H., McNeela, Edel A., Longet, Stephanie, Tobias, Joshua, Aversa, Vincenzo, McEntee, Craig P., Rosa, Monica, Coulter, Ivan S., Holmgren, Jan, Lavelle, Ed C.

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 2.20 MB

english, 2016

34

Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages

Hughes, Caroline S., Colhoun, Liza M., Bains, Baljinder K., Kilgour, Joanne D., Burden, Roberta E., Burrows, James F., Lavelle, Ed C., Gilmore, Brendan F., Scott, Christopher J.

Journal:

Particle and Fibre Toxicology

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

35

Modulation of Immune Responses by Particulate Materials

Lebre, Filipa, Hearnden, Claire H., Lavelle, Ed C.

Journal:

Advanced Materials

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

36

Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer

Schwartz, Christian, O'Grady, Katie, Lavelle, Ed C., Fallon, Padraic G.

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 780 KB

english, 2016

37

Hippo interferes with antiviral defences

Muñoz-Wolf, Natalia, Lavelle, Ed C.

Journal:

Nature Cell Biology

Year:

2017

Language:

english

File:

PDF, 262 KB

english, 2017

38

Industrial grade 2D molybdenum disulphide (MoS 2 ): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation

Moore, Caroline, Movia, Dania, Smith, Ronan J, Hanlon, Damien, Lebre, Filipa, Lavelle, Ed C, Byrne, Hugh J, Coleman, Jonathan N, Volkov, Yuri, McIntyre, Jennifer

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

39

Therapeutic Potential of Carbohydrates as Regulators of Macrophage Activation

Lundahl, Mimmi L.E., Scanlan, Eoin M., Lavelle, Ed C.

Journal:

Biochemical Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

40

Thermostability of the coating, antigen and immunostimulator in an adjuvanted oral capsule vaccine formulation

Longet, Stephanie, Aversa, Vincenzo, O’Donnell, Daire, Tobias, Joshua, Rosa, Monica, Holmgren, Jan, Coulter, Ivan S., Lavelle, Ed C.

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017

41

Targeted strategies for mucosal vaccination

Longet, Stephanie, Lundahl, Mimmi L.E, Lavelle, Ed

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

42

The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses

Oleszycka, Ewa, McCluskey, Sean, Sharp, Fiona A., Muñoz-Wolf, Natalia, Hams, Emily, Gorman, Aoife L., Fallon, Padraic G., Lavelle, Ed C.

Journal:

European Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

43

A Guide to IL-1 family cytokines in adjuvanticity

Muñoz-Wolf, Natalia, Lavelle, Ed C.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

44

Polymyxin B Inadequately Quenches the Effects of Contaminating Lipopolysaccharide on Murine Dendritic Cells

Tynan, Graham A., McNaughton, Anne, Jarnicki, Andrew, Tsuji, Takao, Lavelle, Ed C., Lenz, Laurel L.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

45

The Role of CD103+ Dendritic Cells in the Intestinal Mucosal Immune System

Ruane, Darren Thomas, Lavelle, Ed Charles

Journal:

Frontiers in Immunology

Year:

2011

Language:

english

File:

PDF, 605 KB

english, 2011

46

Editorial: Immune Cells in the Mucosa

Pandiyan, Pushpa, Lavelle, Ed C.

Journal:

Frontiers in Immunology

Year:

2016

Language:

english

File:

PDF, 105 KB

english, 2016

47

Alum Activates the Bovine NLRP3 Inflammasome

Harte, Ciaran, Gorman, Aoife L., McCluskey, S., Carty, Michael, Bowie, Andrew G., Scott, C. J., Meade, Kieran G., Lavelle, Ed C.

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 2.88 MB

english, 2017

48

Editorial overview: Immunomodulation: Striking the right balance: using immunomodulators to target infectious diseases, cancer, and autoimmunity

Lavelle, Ed C, McLachlan, James B

Journal:

Current Opinion in Pharmacology

Year:

2018

File:

PDF, 305 KB

2018

49

Editorial overview: Immunomodulation: Striking the right balance: using immunomodulators to target infectious diseases, cancer, and autoimmunity

Lavelle, Ed C, McLachlan, James B

Journal:

Current Opinion in Pharmacology

Year:

2018

Language:

english

File:

PDF, 305 KB

english, 2018

50

Immunomodulatory properties of chitosan polymers

Moran, Hannah B.T., Turley, Joanna L., Andersson, Mats, Lavelle, Ed C.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.30 MB

english, 2018